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Rabbit anti-Human LMOD1 Polyclonal Antibody

The antibody against LMOD1 was raised in rabbit using the Human LMOD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-52857A

The antibody against LMOD1 was raised in rabbit using the Human LMOD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-52857A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLMOD1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman LMOD1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP29536
Background Information
  • Uniprot Id

    P29536

  • Target Species

    Human

  • Target Name

    LMOD1

  • Target Full Name

    Leiomodin-1

  • Target Function

    Mediates nucleation of actin filaments.

  • Target Subcellular Location

    Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton.

  • Target Protein Families

    Tropomodulin family

  • Target Tissue Specificity

    Detected in lung vascular smooth muscle (at protein level). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle. Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine.

  • Target Synonyms

    1D; 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; 9530015K06Rik; D1; Leiomodin; Leiomodin-1; Lmod1; LMOD1_HUMAN; muscle form; SM LMOD; SM-Lmod; SMLMOD; Smooth muscle leiomodin; Thyroid associated ophthalmopathy autoantigen ; Thyroid-associated ophthalmopathy autoantigen

  • Target Background

    The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy.

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