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The antibody against LY6H was raised in rabbit using the Recombinant Human Lymphocyte antigen 6H protein (26-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against LY6H was raised in rabbit using the Recombinant Human Lymphocyte antigen 6H protein (26-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry analysis of human testis tissue using LY6H Antibody at dilution of 1:100
Immunohistochemistry analysis of human tonsil tissue using LY6H Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using LY6H Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-21892A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LY6H |
| Target Synonyms | LY6HLymphocyte antigen 6H antibody; Ly-6H antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Lymphocyte antigen 6H protein (26-115AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O94772 |
Uniprot Id
O94772
Target Species
Human
Target Name
LY6H
Target Full Name
Lymphocyte antigen 6H
Target Function
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Tissue Specificity
Highly expressed in brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. Also found in lower levels in testis, pancreas, small intestine and colon.
Target Research Area
Cell Biology
Target Synonyms
LY6HLymphocyte antigen 6H; Ly-6H
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