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Rabbit anti-Human MARCH5 Polyclonal Antibody

The antibody against MARCH5 was raised in rabbit using the Human MARCH5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51210A

The antibody against MARCH5 was raised in rabbit using the Human MARCH5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-51210A ClonalityPolyclonal
Host SpeciesRabbitTarget Name5-Mar
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman MARCH5Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NX47
Background Information
  • Uniprot Id

    Q9NX47

  • Target Species

    Human

  • Target Name

    MARCHF5

  • Target Full Name

    E3 ubiquitin-protein ligase MARCHF5

  • Target Function

    Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1.

  • Target Subcellular Location

    Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Tissue Specificity

    Expressed in brain, heart, liver, lung, spleen, stomach, testis, skeletal and muscle.

  • Target Synonyms

    MARCHF5; MARCH5; RNF153; E3 ubiquitin-protein ligase MARCHF5; Membrane-associated RING finger protein 5; Membrane-associated RING-CH protein V; MARCH-V; Mitochondrial ubiquitin ligase; MITOL; RING finger protein 153; RING-type E3 ubiquitin transferase MARCHF5

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