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The antibody against ME3 was raised in rabbit using the Recombinant Human NADP-dependent malic enzyme, mitochondrial protein (547-598AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ME3 was raised in rabbit using the Recombinant Human NADP-dependent malic enzyme, mitochondrial protein (547-598AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using ME3 Antibody at dilution of 1:1002
| Cat.No | ADC-15459A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ME3 |
| Target Synonyms | ME3NADP-dependent malic enzyme antibody; mitochondrial antibody; NADP-ME antibody; EC 1.1.1.40 antibody; Malic enzyme 3 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human NADP-dependent malic enzyme, mitochondrial protein (547-598AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16798 |
Uniprot Id
Q16798
Target Species
Human
Target Name
ME3
Target Full Name
NADP-dependent malic enzyme, mitochondrial
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Malic enzymes family
Target Tissue Specificity
Expressed predominantly in organs with a low-division rate.
Target Research Area
others
Target Synonyms
ME3NADP-dependent malic enzyme; mitochondrial; NADP-ME; EC 1.1.1.40; Malic enzyme 3
Target Background
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
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