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Rabbit anti-Human MED13L Polyclonal Antibody

The antibody against MED13L was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TRAP240. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-35804A

The antibody against MED13L was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TRAP240. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-35804A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMED13L
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human TRAP240.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ71F56
Background Information
  • Uniprot Id

    Q71F56

  • Target Species

    Human

  • Target Name

    MED13L

  • Target Full Name

    Mediator of RNA polymerase II transcription subunit 13-like

  • Target Function

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

  • Target Involvement

    Transposition of the great arteries dextro-looped 1 (DTGA1); Mental retardation and distinctive facial features with or without cardiac defects (MRFACD)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Mediator complex subunit 13 family

  • Target Tissue Specificity

    Highly expressed in brain (cerebellum), heart (aorta), skeletal muscle, kidney, placenta and peripheral blood leukocytes. Highly expressed in fetal brain.

  • Target Synonyms

    MD13L_HUMAN; MED13L; Mediator complex subunit 13 like; Mediator complex subunit 13-like; Mediator of RNA polymerase II transcription subunit 13-like; THRAP2; Thyroid hormone receptor-associated protein 2; Thyroid hormone receptor-associated protein complex 240 kDa component-like; TRAP240L

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