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The antibody against MED6 was raised in rabbit using the Recombinant Human Mediator of RNA polymerase II transcription subunit 6 protein (27-246AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against MED6 was raised in rabbit using the Recombinant Human Mediator of RNA polymerase II transcription subunit 6 protein (27-246AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-40229A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MED6 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Mediator of RNA polymerase II transcription subunit 6 protein (27-246AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75586 |
Uniprot Id
O75586
Target Species
Human
Target Name
MED6
Target Full Name
Mediator of RNA polymerase II transcription subunit 6
Target Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Target Subcellular Location
Nucleus.
Target Protein Families
Mediator complex subunit 6 family
Target Synonyms
Activator recruited cofactor 33 kDa; Activator-recruited cofactor 33 kDa component; ARC33; hMed6; MED6; MED6_HUMAN; Mediator complex subunit 6; Mediator of RNA polymerase II transcription subunit 6; NY REN 28; NY REN 28 antigen; Renal carcinoma antigen NY-REN-28; RNA polymerase transcriptional regulation mediator subunit 6
Target Background
Enables transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of mediator complex.
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