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Rabbit anti-Human MEOX2 Polyclonal Antibody

The antibody against MEOX2 was raised in rabbit using the Synthesized peptide derived from internal of Human MEOX2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-42048A

The antibody against MEOX2 was raised in rabbit using the Synthesized peptide derived from internal of Human MEOX2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-42048A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMEOX2
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human MEOX2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP50222
Background Information
  • Uniprot Id

    P50222

  • Target Species

    Human

  • Target Name

    MEOX2

  • Target Full Name

    Homeobox protein MOX-2

  • Target Function

    Mesodermal transcription factor that plays a key role in somitogenesis and somitogenesis and limb muscle differentiation. Required during limb development for normal appendicular muscle formation and for the normal regulation of myogenic genes. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. Also acts as a negative regulator of angiogenesis. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Together with TCF15, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells.

  • Target Subcellular Location

    Nucleus. Nucleus speckle.

  • Target Synonyms

    GAX ; Growth arrest-specific homeobox; Homeobox protein MOX 2 ; Homeobox protein MOX-2; meox2; MEOX2_HUMAN; Mesenchyme homeobox 2; MOX2

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