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The antibody against MESP2 was raised in rabbit using the Recombinant Human Mesoderm posterior protein 2 protein (218-397AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
The antibody against MESP2 was raised in rabbit using the Recombinant Human Mesoderm posterior protein 2 protein (218-397AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-16256A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MESP2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Mesoderm posterior protein 2 protein (218-397AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q0VG99 |
Uniprot Id
Q0VG99
Target Species
Human
Target Name
MESP2
Target Full Name
Mesoderm posterior protein 2
Target Function
Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
Target Involvement
Spondylocostal dysostosis 2, autosomal recessive (SCDO2)
Target Subcellular Location
Nucleus.
Target Synonyms
Basic helix loop helix protein MESP 2; Basic helix loop helix protein MESP2; BHLH protein MesP2; bHLHc6; Class C basic helix-loop-helix protein 6; Hypothetical class II basic helix loop helix protein MESP 2; Hypothetical class II basic helix loop helix protein MESP2; Mesoderm posterior 2; mesoderm posterior 2 homolog (mouse); Mesoderm posterior 2 homolog; Mesoderm posterior protein 2; Mesp 2; MESP2; MESP2_HUMAN; SCDO 2; SCDO2
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