Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against METTL5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human METTL5 (NP_054887.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against METTL5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human METTL5 (NP_054887.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01024A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | METTL5 |
| Target Synonyms | MRT72; HSPC133; METTL5 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Mouse liver, Rat liver, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human METTL5 (NP_054887.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NRN9 | Immunogen Sequence |
Uniprot Id
Q9NRN9
Target Species
Human
Target Name
METTL5
Target Full Name
rRNA N(6)-adenosine-methyltransferase METTL5
Target Function
Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA. N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation.
Target Subcellular Location
Nucleus. Cell junction, synapse, presynapse. Cell junction, synapse, postsynapse.
Target Protein Families
Methyltransferase superfamily, PrmA family
Target Tissue Specificity
Expressed from very early development (8 post-conceptual weeks) and expression persists through adulthood in multiple substructures of the brain, including the cerebellar cortex, hippocampus, and striatum.
Target Synonyms
2810410A08Rik; DC3; FLJ10459; HSPC133; mCG_12967; Methyltransferase like protein 5; Methyltransferase-like protein 5; METL5_HUMAN; METTL 5; METTL5; MGC187943; OTTHUMP00000205107; OTTHUMP00000205108; OTTHUMP00000205109; OTTMUSP00000040951; RGD1566062
Target Background
Enables S-adenosyl-L-methionine binding activity and rRNA (adenine-N6-)-methyltransferase activity. Involved in positive regulation of translation and rRNA methylation. Located in nucleus; postsynapse; and presynapse. Implicated in autosomal recessive intellectual developmental disorder-72.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
