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The antibody against MOK was raised in rabbit using the Synthesized peptide derived from the Internal region of Human RAGE. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against MOK was raised in rabbit using the Synthesized peptide derived from the Internal region of Human RAGE. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
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Western Blot analysis of 293 cells using RAGE Polyclonal Antibody
| Cat.No | ADC-37737A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MOK |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human RAGE. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UQ07 |
Uniprot Id
Q9UQ07
Target Species
Human
Target Name
MOK
Target Full Name
MAPK/MAK/MRK overlapping kinase
Target Function
Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.
Target Subcellular Location
Cytoplasm. Cell projection, cilium. Nucleus.
Target Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Target Tissue Specificity
Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina.
Target Synonyms
Antigen recognized by autologous cytolytic T lymphocytes; EC 2.7.11.22; LE 9211 A antigen; MAPK/MAK/MRK overlapping kinase; MOK; MOK protein kinase; MOK_HUMAN; RAGE 1; RAGE; RAGE-1; RAGE1; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; Renal tumor antigen; STK30
Target Background
This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
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