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Rabbit anti-Human MRPL17 Polyclonal Antibody

The antibody against MRPL17 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human MRP-L17. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

ADC-34167A

The antibody against MRPL17 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human MRP-L17. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-34167A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL17
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human MRP-L17.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NRX2
Background Information
  • Uniprot Id

    Q9NRX2

  • Target Species

    Human

  • Target Name

    MRPL17

  • Target Full Name

    Large ribosomal subunit protein bL17m

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Bacterial ribosomal protein bL17 family

  • Target Tissue Specificity

    Detected in adrenal gland, mammary gland and adipose tissue.

  • Target Synonyms

    MRPL17; LIP2; 39S ribosomal protein L17; mitochondrial; L17mt; MRP-L17; LYST-interacting protein 2; Mitochondrial large ribosomal subunit protein bL17m

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

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