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Rabbit anti-Human MRPS14 Polyclonal Antibody

The antibody against MRPS14 was raised in rabbit using the Recombinant Human 28S ribosomal protein S14, mitochondrial protein (1-128AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-24368A

The antibody against MRPS14 was raised in rabbit using the Recombinant Human 28S ribosomal protein S14, mitochondrial protein (1-128AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-24368A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPS14
Target SynonymsMRPS14 antibody; 28S ribosomal protein S14 antibody; mitochondrial antibody; MRP-S14 antibody; S14mt antibody; Mitochondrial small ribosomal subunit protein uS14m antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human 28S ribosomal protein S14, mitochondrial protein (1-128AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO60783
Background Information
  • Uniprot Id

    O60783

  • Target Species

    Human

  • Target Name

    MRPS14

  • Target Full Name

    Small ribosomal subunit protein uS14m

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Universal ribosomal protein uS14 family

  • Target Synonyms

    MRPS14; 28S ribosomal protein S14; mitochondrial; MRP-S14; S14mt; Mitochondrial small ribosomal subunit protein uS14m

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants.

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