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The antibody against MT-ND5 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ND5. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against MT-ND5 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ND5. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of HT29 cells using ND5 Polyclonal Antibody
| Cat.No | ADC-38131A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MT-ND5 |
| Target Synonyms | Complex I, subunit ND5 antibody; NADH ubiquinone oxidoreductase chain 5 antibody; NADH-ubiquinone oxidoreductase chain 5 antibody; NADH5 antibody; ND5 antibody; NU5M_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human ND5. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P03915 |
Uniprot Id
P03915
Target Species
Human
Target Name
MT-ND5
Target Full Name
NADH-ubiquinone oxidoreductase chain 5
Target Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Target Involvement
Leber hereditary optic neuropathy (LHON); Leigh syndrome (LS); Mitochondrial complex I deficiency (MT-C1D); Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
Complex I subunit 5 family
Target Synonyms
Complex I, subunit ND5; EC 1.6.5.3; Mitochondrially encoded NADH dehydrogenase 5; MT ND5; MT-ND5; MTND 5; MTND5; NAD5; NADH dehydrogenase subunit 5 (complex I); NADH dehydrogenase subunit 5; NADH ubiquinone oxidoreductase , subunit ND5; NADH ubiquinone oxidoreductase chain 5; NADH-ubiquinone oxidoreductase chain 5; NADH5; ND5; NU5M_HUMAN
Target Background
Contributes to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in central nervous system; heart; liver; metanephros; and retina. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5).
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