Rabbit anti-Human MYL12B Polyclonal Antibody

The antibody against MYL12B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human MYL12B (NP_291024.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03859A

Number

Cat.No	ADA-03859A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MYL12B
Target Synonyms	MLC-B; MRLC2; MYL12B	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse lung	Application	ELISA, WB

Cat.No

ADA-03859A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MYL12B

Target Synonyms

MLC-B; MRLC2; MYL12B

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse lung

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human MYL12B (NP_291024.1).	Target Species	Human
Immunogen Sequence	MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD	Uniprot ID	O14950

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human MYL12B (NP_291024.1).

Target Species

Human

Immunogen Sequence

MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD

Uniprot ID

O14950

Background Information

Uniprot Id

O14950
Target Species

Human
Target Name

MYL12B
Target Full Name

Myosin regulatory light chain 12B
Target Function

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.
Target Tissue Specificity

Ubiquitously expressed in various hematopoietic cells.
Target Research Area

Others
Target Synonyms

ML12B_HUMAN; MLC 2A; MLC-2; MLC-2a; MLC-B; MLC20; MRLC2; MYL12B; MYLC2B; Myosin light chain 12B regulatory; Myosin regulatory light chain 12B; myosin regulatory light chain 2; Myosin regulatory light chain 2-B; myosin regulatory light chain 2-B; smooth muscle isoform; Myosin regulatory light chain 20 kDa; Myosin regulatory light chain MRLC2; myosin; light chain 12B; regulatory; OTTHUMP00000162244; OTTHUMP00000165806; OTTHUMP00000165807; OTTHUMP00000165808; SHUJUN-1; smooth muscle isoform
Target Background

The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).

Rabbit anti-Human MYL12B Polyclonal Antibody

Specifications

Immunogen Information

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