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Rabbit anti-Human MYO18B Polyclonal Antibody

The antibody against MYO18B was raised in rabbit using the Synthetic peptide of Human MYO18B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-26323A

The antibody against MYO18B was raised in rabbit using the Synthetic peptide of Human MYO18B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-26323A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMYO18B
Target SynonymsBK125H2.1 antibody; DKFZp434C2422 antibody; DKFZp779C1668 antibody; MY18B_HUMAN antibody; MYO18B antibody; myosin 18B antibody; myosin XVIIIB antibody; Myosin-XVIIIb antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human MYO18BTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8IUG5
Background Information
  • Uniprot Id

    Q8IUG5

  • Target Species

    Human

  • Target Name

    MYO18B

  • Target Full Name

    Unconventional myosin-XVIIIb

  • Target Function

    May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.

  • Target Involvement

    Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism (KFS4)

  • Target Subcellular Location

    Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family

  • Target Tissue Specificity

    Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.

  • Target Synonyms

    BK125H2.1; DKFZp434C2422; DKFZp779C1668; MY18B_HUMAN; MYO18B; myosin 18B ; myosin XVIIIB; Myosin-XVIIIb

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