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The antibody against MYO9B was raised in rabbit using the Synthesized peptide derived from N-terminal of Human MYO9B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against MYO9B was raised in rabbit using the Synthesized peptide derived from N-terminal of Human MYO9B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from HeLa cells and Jurkat cells, using MYO9B antibody.
| Cat.No | ADC-41112A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYO9B |
| Target Synonyms | MYO9B antibody; MYR5 antibody; Unconventional myosin-IXb antibody; Unconventional myosin-9b antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from N-terminal of Human MYO9B. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13459 |
Uniprot Id
Q13459
Target Species
Human
Target Name
MYO9B
Target Full Name
Unconventional myosin-IXb
Target Function
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activator for RHOA. Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1; interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA.
Target Involvement
Celiac disease 4 (CELIAC4)
Target Subcellular Location
Cytoplasm, cell cortex. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton.
Target Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
Target Tissue Specificity
Detected in peripheral blood leukocytes (at protein level). Expressed predominantly in peripheral blood leukocytes and at lower levels, in thymus, spleen, testis, prostate, ovary, brain, small intestine and lung.
Target Synonyms
MYO9B; MYR5; Unconventional myosin-IXb; Unconventional myosin-9b
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