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Rabbit anti-Human MYT1 Polyclonal Antibody

The antibody against MYT1 was raised in rabbit using the Recombinant Human Myelin transcription factor 1 protein (317-451AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-07851A

The antibody against MYT1 was raised in rabbit using the Recombinant Human Myelin transcription factor 1 protein (317-451AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-07851A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMYT1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Myelin transcription factor 1 protein (317-451AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ01538
Background Information
  • Uniprot Id

    Q01538

  • Target Species

    Human

  • Target Name

    MYT1

  • Target Full Name

    Myelin transcription factor 1

  • Target Function

    Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    MYT1 family

  • Target Tissue Specificity

    Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.

  • Target Research Area

    Developmental Biology

  • Target Synonyms

    C20orf36; KIAA0835; KIAA1050; MTF1; Myelin transcription factor 1; Myelin transcription factor I; MYT1; MYT1_HUMAN; MyTI; PLPB1; Proteolipid protein-binding protein

  • Target Background

    The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.

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