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Rabbit anti-Human NANOS3 Polyclonal Antibody

The antibody against NANOS3 was raised in rabbit using the Human NANOS3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-47871A

The antibody against NANOS3 was raised in rabbit using the Human NANOS3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-47871A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNANOS3
Target SynonymsNANO3_HUMAN antibody; Nanos homolog 3 antibody; NANOS3 antibody; NOS-3 antibody; Nos3 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NANOS3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP60323
Background Information
  • Uniprot Id

    P60323

  • Target Species

    Human

  • Target Name

    NANOS3

  • Target Full Name

    Nanos homolog 3

  • Target Function

    Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.

  • Target Subcellular Location

    Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body.

  • Target Protein Families

    Nanos family

  • Target Tissue Specificity

    Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, ty

  • Target Synonyms

    NANO3_HUMAN; Nanos homolog 3; NANOS3; NOS-3; Nos3

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