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Rabbit anti-Human NCLN Polyclonal Antibody

The antibody against NCLN was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Nicalin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-34437A

The antibody against NCLN was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Nicalin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-34437A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNCLN
Target SynonymsNCLN antibody; NCLN_HUMAN antibody; NET59 antibody; Nicalin antibody; Nicalin homolog (zebrafish) antibody; Nicastrin like protein antibody; Nicastrin-like protein antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human Nicalin.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ969V3
Background Information
  • Uniprot Id

    Q969V3

  • Target Species

    Human

  • Target Name

    NCLN

  • Target Full Name

    BOS complex subunit NCLN

  • Target Function

    Component of a ribosome-associated translocon complex involved in multi-pass membrane protein transport into the endoplasmic reticulum (ER) membrane and biogenesis. May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NOMO.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    Nicastrin family

  • Target Tissue Specificity

    Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.

  • Target Synonyms

    NCLN; NCLN_HUMAN; NET59; Nicalin; Nicalin homolog (zebrafish); Nicastrin like protein; Nicastrin-like protein

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