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Rabbit anti-Human NF1 Polyclonal Antibody

The antibody against NF1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Neurofibromin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.

ADC-38107A

The antibody against NF1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Neurofibromin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-38107A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNF1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human Neurofibromin.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP21359
Background Information
  • Uniprot Id

    P21359

  • Target Species

    Human

  • Target Name

    NF1

  • Target Full Name

    Neurofibromin

  • Target Function

    Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.

  • Target Involvement

    Neurofibromatosis 1 (NF1); Leukemia, juvenile myelomonocytic (JMML); Watson syndrome (WTSN); Familial spinal neurofibromatosis (FSNF); Neurofibromatosis-Noonan syndrome (NFNS); Colorectal cancer (CRC)

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Tissue Specificity

    Detected in brain, peripheral nerve, lung, colon and muscle.

  • Target Research Area

    Cancer

  • Target Synonyms

    DKFZp686J1293; FLJ21220; Neurofibromatosis Noonan syndrome; Neurofibromatosis related protein NF 1; Neurofibromatosis related protein NF1; neurofibromatosis type I; Neurofibromatosis-related protein NF-1; Neurofibromin 1; Neurofibromin truncated; Neurofibromin1; NF 1; NF; NF1; NF1_HUMAN; NFNS; Type 1 Neurofibromatosis; von Recklinghausen disease neurofibromin; von Recklinghausen disease related protein VRNF; VRNF; WATS; Watson disease related protein WSS; Watson syndrome; WSS

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