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The antibody against NFKBIL1 was raised in rabbit using the Recombinant Human NF-kappa-B inhibitor-like protein 1 protein (185-312AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against NFKBIL1 was raised in rabbit using the Recombinant Human NF-kappa-B inhibitor-like protein 1 protein (185-312AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-04551A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFKBIL1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human NF-kappa-B inhibitor-like protein 1 protein (185-312AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UBC1 |
Uniprot Id
Q9UBC1
Target Species
Human
Target Name
NFKBIL1
Target Full Name
NF-kappa-B inhibitor-like protein 1
Target Function
Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli.
Target Involvement
Rheumatoid arthritis (RA)
Target Subcellular Location
Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus.
Target Tissue Specificity
Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes.
Target Synonyms
NFKBIL1; IKBL; NF-kappa-B inhibitor-like protein 1; Inhibitor of kappa B-like protein; I-kappa-B-like protein; IkappaBL; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Target Background
This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene.
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