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Rabbit anti-Human NME6 Polyclonal Antibody

The antibody against NME6 was raised in rabbit using the Fusion protein of Human NME6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-31597A

The antibody against NME6 was raised in rabbit using the Fusion protein of Human NME6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-31597A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNME6
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human NME6Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO75414
Background Information
  • Uniprot Id

    O75414

  • Target Species

    Human

  • Target Name

    NME6

  • Target Full Name

    Nucleoside diphosphate kinase 6

  • Target Function

    Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.

  • Target Protein Families

    NDK family

  • Target Tissue Specificity

    Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.

  • Target Synonyms

    Inhibitor of p53 induced apoptosis alpha ; Inhibitor of p53-induced apoptosis-alpha; IPIA ALPHA; IPIA-alpha; NDK 6; NDK6_HUMAN; NDP kinase 6; NM23 H6 ; nm23-H6; NM23H6 ; Nme6; Nucleoside diphosphate kinase 6; OTTHUMP00000164810; OTTHUMP00000210736; OTTHUMP00000210737; OTTHUMP00000210738; OTTHUMP00000210741; OTTHUMP00000210742; OTTHUMP00000210744; OTTHUMP00000210745

  • Target Background

    Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).

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