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The antibody against NME7 was raised in rabbit using the Recombinant Human Nucleoside diphosphate kinase 7 protein (1-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against NME7 was raised in rabbit using the Recombinant Human Nucleoside diphosphate kinase 7 protein (1-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using NME7 Antibody at dilution of 1:1002
| Cat.No | ADC-24253A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NME7 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Nucleoside diphosphate kinase 7 protein (1-150AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y5B8 |
Uniprot Id
Q9Y5B8
Target Species
Human
Target Name
NME7
Target Full Name
Nucleoside diphosphate kinase homolog 7
Target Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Target Protein Families
NDK family
Target Synonyms
MN23H7; NDK 7; NDK7_HUMAN; NDP kinase 7; nm23 H7 ; nm23-H7; NME/NM23 family member 7; Nme7; Non metastatic cells 7 protein expressed in (nucleoside diphosphate kinase); Nucleoside diphosphate kinase 7
Target Background
This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants.
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