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The antibody against NPFF was raised in rabbit using the Recombinant Human Pro-FMRFamide-related neuropeptide FF protein (34-113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against NPFF was raised in rabbit using the Recombinant Human Pro-FMRFamide-related neuropeptide FF protein (34-113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human small intestine tissue using NPFF Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using NPFF Antibody at dilution of 1:1002
| Cat.No | ADC-17360A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NPFF |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Pro-FMRFamide-related neuropeptide FF protein (34-113AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15130 |
Uniprot Id
O15130
Target Species
Human
Target Name
NPFF
Target Full Name
Pro-FMRFamide-related neuropeptide FF
Target Function
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
Target Subcellular Location
Secreted.
Target Protein Families
FARP (FMRFamide related peptide) family
Target Research Area
Neuroscience
Target Synonyms
NPFF; Pro-FMRFamide-related neuropeptide FF; FMRFamide-related peptides) [Cleaved into: Neuropeptide SF; NPSF); Neuropeptide FF; NPFF); Neuropeptide AF; NPAF)]
Target Background
This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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