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The antibody against NUP88 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 502-741 of human NUP88 (NP_002523.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NUP88 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 502-741 of human NUP88 (NP_002523.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07619A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NUP88 |
| Target Synonyms | FADS4; NUP88 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, NCI-H460, Rat testis, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 502-741 of human NUP88 (NP_002523.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q99567 | Immunogen Sequence |
Uniprot Id
Q99567
Target Species
Human
Target Name
NUP88
Target Full Name
Nuclear pore complex protein Nup88
Target Function
Component of nuclear pore complex.
Target Subcellular Location
Nucleus, nuclear pore complex.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
88 kDa nucleoporin; karyoporin; Nuclear pore complex protein 88; Nuclear pore complex protein Nup88; Nuclear pore complex protein88; Nucleoporin 88; Nucleoporin 88 kDa; Nucleoporin 88kDa; Nucleoporin Nup88; Nucleoporin88; Nucleoporin88kDa; Nup 84; NUP 88; Nup84; NUP88; NUP88_HUMAN; Prei 2; Prei2; Preimplantation protein 2; Preimplantation protein2
Target Background
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.
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