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The antibody against OASL was raised in rabbit using the Synthesized peptide derived from Human OASL. at AA range: 1-50 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against OASL was raised in rabbit using the Synthesized peptide derived from Human OASL. at AA range: 1-50 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
| Cat.No | ADC-12917A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OASL |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human OASL. at AA range: 1-50 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15646 |
Uniprot Id
Q15646
Target Species
Human
Target Name
OASL
Target Full Name
2'-5'-oligoadenylate synthase-like protein
Target Function
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Target Subcellular Location
[Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.
Target Protein Families
2-5A synthase family
Target Tissue Specificity
Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
Target Research Area
Cell Biology
Target Synonyms
2' 5' oligoadenylate synthetase like; 2''-5''-OAS-related protein; 2''-5''-OAS-RP; 2''-5''-oligoadenylate synthase-like protein; 2'-5' oligoadenylate synthetase-like 2; 2'-5'-oligoadenylate synthetase-like; 59 kDa 2' 5' oligoadenylate synthetase like protein; 59 kDa 2''-5''-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein; M1204; Mmu-OASL; OASL; OASL_HUMAN; Oasl2; p59 OASL; p59OASL; THYROID HORMONE RECEPTOR INTERACTOR 14; Thyroid receptor interacting protein 14; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP-14; TRIP14
Target Background
Enables DNA binding activity and double-stranded RNA binding activity. Involved in several processes, including interleukin-27-mediated signaling pathway; negative regulation of viral genome replication; and positive regulation of RIG-I signaling pathway. Located in cytosol; nucleolus; and nucleoplasm.
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