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The antibody against OAT was raised in rabbit using the Synthesized peptide derived from the Internal region of Human OAT. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against OAT was raised in rabbit using the Synthesized peptide derived from the Internal region of Human OAT. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
| Cat.No | ADC-34839A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OAT |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human OAT. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04181 |
Uniprot Id
P04181
Target Species
Human
Target Name
OAT
Target Full Name
Ornithine aminotransferase, mitochondrial
Target Function
Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate.
Target Involvement
Hyperornithinemia with gyrate atrophy of choroid and retina (HOGA)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-III pyridoxal-phosphate-dependent aminotransferase family
Target Synonyms
OAT; Ornithine aminotransferase; mitochondrial; EC 2.6.1.13; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase; hepatic form; Ornithine aminotransferase; renal form]
Target Background
This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
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