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Rabbit anti-Human OLIG1 Polyclonal Antibody

The antibody against OLIG1 was raised in rabbit using the Recombinant Human Oligodendrocyte transcription factor 1 protein (17-105AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-08887A

The antibody against OLIG1 was raised in rabbit using the Recombinant Human Oligodendrocyte transcription factor 1 protein (17-105AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-08887A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOLIG1
FormLiquidSpecies ReactivityHuman, Rat
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Oligodendrocyte transcription factor 1 protein (17-105AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8TAK6
Background Information
  • Uniprot Id

    Q8TAK6

  • Target Species

    Human

  • Target Name

    OLIG1

  • Target Full Name

    Oligodendrocyte transcription factor 1

  • Target Function

    Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    Basic domain helix loop helix protein class B 6; Basic domain helix loop helix protein class B6; BHLH B6; BHLHB 6; bHLHb6; bHLHe21; Class B basic helix-loop-helix protein 6; Class E basic helix-loop-helix protein 21; Olig 1; Olig1; OLIG1_HUMAN; Oligo 1; Oligo1; Oligodendrocyte lineage transcription factor 1; Oligodendrocyte specific bHLH transcription factor 1; Oligodendrocyte transcription factor 1

  • Target Background

    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuron fate commitment. Predicted to be part of chromatin. Predicted to be active in nucleus.

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