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The antibody against OR51E2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PSGR. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
The antibody against OR51E2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PSGR. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
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| Cat.No | ADC-33687A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OR51E2 |
| Target Synonyms | OR51E2; PSGR; Olfactory receptor 51E2; HPRAJ; Olfactory receptor OR11-16; Prostate-specific G-protein coupled receptor | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human PSGR. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H255 |
Uniprot Id
Q9H255
Target Species
Human
Target Name
OR51E2
Target Full Name
Olfactory receptor 51E2
Target Function
Olfactory receptor. Activated by the odorant, beta-ionone, a synthetic terpenoid. The activity of this receptor is propably mediated by G-proteins leading to the elevation of intracellular Ca(2+), cAMP and activation of the protein kinases PKA and MAPK3/MAPK1. Stimulation of OR51E2 by beta-ionone affects melanocyte proliferation, differentiation, and melanogenesis. Activation of OR51E2 by beta-ionone increases proliferation and migration of primary retinal pigment epithelial (RPE) cells. Activated also by the short-chain fatty acids (SCFA) acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure. May also be activated by steroid hormones and regulate cell proliferation. Activated by L-lactate in glomus cells.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Highly expressed in the prostate. Also expressed in spleen, liver, olfactory epithelium, retinal pigment epithelium and medulla oblongata. In the retinal pigment epithelium expression is restricted to the pigment cells and choroid (at protein level). Expr
Target Research Area
Others
Target Synonyms
OR51E2; PSGR; Olfactory receptor 51E2; HPRAJ; Olfactory receptor OR11-16; Prostate-specific G-protein coupled receptor
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