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Rabbit anti-Human ORC4 Polyclonal Antibody

The antibody against ORC4 was raised in rabbit using the Recombinant Human Origin recognition complex subunit 4 protein (187-436AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-40281A

The antibody against ORC4 was raised in rabbit using the Recombinant Human Origin recognition complex subunit 4 protein (187-436AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-40281A ClonalityPolyclonal
Host SpeciesRabbitTarget NameORC4
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Origin recognition complex subunit 4 protein (187-436AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO43929
Background Information
  • Uniprot Id

    O43929

  • Target Species

    Human

  • Target Name

    ORC4

  • Target Full Name

    Origin recognition complex subunit 4

  • Target Function

    Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

  • Target Involvement

    Meier-Gorlin syndrome 2 (MGORS2)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ORC4 family

  • Target Research Area

    Transcription

  • Target Synonyms

    Origin recognition complex; subunit 4; S. cerevisiae; homolog of; FLJ46668; HSORC4; ORC 4; ORC 4L; ORC 4P; ORC4; ORC4_HUMAN; ORC4L; ORC4L protein; ORC4P; Origin recognition complex subunit 4 (yeast homolog) like; Origin recognition complex subunit 4; Origin recognition complex subunit 4 like (yeast); Origin recognition complex subunit 4 like; origin recognition complex; subunit 4 homolog; Origin recognition complex; subunit 4; S. cerevisiae; homolog-like

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