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The antibody against ORMDL3 was raised in rabbit using the Recombinant Human ORM1-like protein 3 protein (43-94AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against ORMDL3 was raised in rabbit using the Recombinant Human ORM1-like protein 3 protein (43-94AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-05493A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ORMDL3 |
| Target Synonyms | ORMDL3; ORM1-like protein 3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Human ORM1-like protein 3 protein (43-94AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N138 |
Uniprot Id
Q8N138
Target Species
Human
Target Name
ORMDL3
Target Full Name
ORM1-like protein 3
Target Function
Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
Target Involvement
Asthma (ASTHMA)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
ORM family
Target Tissue Specificity
Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus.
Target Synonyms
ORMDL3; ORM1-like protein 3
Target Background
Involved in ceramide metabolic process. Acts upstream of or within several processes, including negative regulation of B cell apoptotic process; negative regulation of ceramide biosynthetic process; and positive regulation of protein localization to nucleus. Located in endoplasmic reticulum. Part of SPOTS complex.
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