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The antibody against OTUD6B was raised in rabbit using the Recombinant Human Deubiquitinase OTUD6B protein (1-293AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against OTUD6B was raised in rabbit using the Recombinant Human Deubiquitinase OTUD6B protein (1-293AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human ovarian cancer using OTUD6B Antibody at dilution of 1:1002
| Cat.No | ADC-24178A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OTUD6B |
| Target Synonyms | CGI-77 antibody; DUBA-5 antibody; DUBA5 antibody; OTU domain containing protein 6B antibody; OTU domain-containing protein 6B antibody; OTU6B_HUMAN antibody; OTUD6B antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Deubiquitinase OTUD6B protein (1-293AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N6M0 |
Uniprot Id
Q8N6M0
Target Species
Human
Target Name
OTUD6B
Target Full Name
Deubiquitinase OTUD6B
Target Function
Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1. May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation. May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation. May also play a role in proteasome assembly and function.; Stimulates protein synthesis. Influences the expression of CCND1/cyclin D1 by promoting its translation and regulates MYC/c-Myc protein stability.
Target Synonyms
CGI-77; DUBA-5; DUBA5; OTU domain containing protein 6B; OTU domain-containing protein 6B; OTU6B_HUMAN; OTUD6B
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