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The antibody against OTX1 was raised in rabbit using the Recombinant Human Homeobox protein OTX1 protein (29-244AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against OTX1 was raised in rabbit using the Recombinant Human Homeobox protein OTX1 protein (29-244AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using OTX1 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using OTX1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-10945A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OTX1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Homeobox protein OTX1 protein (29-244AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P32242 |
Uniprot Id
P32242
Target Species
Human
Target Name
OTX1
Target Full Name
Homeobox protein OTX1
Target Function
Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Target Subcellular Location
Nucleus.
Target Protein Families
Paired homeobox family, Bicoid subfamily
Target Tissue Specificity
Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level).
Target Synonyms
FLJ38361; Homeobox protein OTX 1; Homeobox protein OTX1; MGC15736; Orthodenticle 1; Orthodenticle homeobox 1; Orthodenticle homolog 1; Orthodenticle1; Otx 1; otx1; OTX1_HUMAN
Target Background
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants.
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