Rabbit anti-Human p150 CAF1 Polyclonal Antibody

The antibody against p150 CAF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human p150 CAF1 (NP_005474.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04376A

Number

Cat.No	ADA-04376A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	p150 CAF1
Target Synonyms	CAF1; P150; CAF-1; CAF1B; CAF1P150; p150 CAF1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, K-562	Application	ELISA, WB

Cat.No

ADA-04376A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

p150 CAF1

Target Synonyms

CAF1; P150; CAF-1; CAF1B; CAF1P150; p150 CAF1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, K-562

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human p150 CAF1 (NP_005474.2).	Target Species	Human
Immunogen Sequence	MLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTSVQSKSPDLEASLDTLENNCHVGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLTEDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETLSDIPCKTEEEGVGCGGAGRRGDSQ	Uniprot ID	Q13111

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human p150 CAF1 (NP_005474.2).

Target Species

Human

Immunogen Sequence

MLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTSVQSKSPDLEASLDTLENNCHVGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLTEDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETLSDIPCKTEEEGVGCGGAGRRGDSQ

Uniprot ID

Q13111

Background Information

Uniprot Id

Q13111
Target Species

Human
Target Name

CHAF1A
Target Full Name

Chromatin assembly factor 1 subunit A
Target Function

Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
Target Subcellular Location

Nucleus. Note=DNA replication foci.
Target Protein Families

CHAF1A family
Target Synonyms

CAF 1; CAF 1 subunit A; CAF; CAF I 150 kDa subunit; CAF I p150; CAF-1 subunit A; CAF-I 150 kDa subunit; CAF-I p150; CAF1; CAF1A_HUMAN; CAF1B; CAF1P150; CHAF1A; Chromatin assembly factor 1 subunit A; Chromatin Assembly Factor 1 Subunit A p150; Chromatin assembly factor I (150 kDa); Chromatin assembly factor I 150 kDa; Chromatin assembly factor I p150 subunit; DCAF1; hp150; MGC71229; P150
Target Background

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).

Rabbit anti-Human p150 CAF1 Polyclonal Antibody

Specifications

Immunogen Information

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