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The antibody against PAH was raised in rabbit using the Recombinant Human Phenylalanine-4-hydroxylase protein (2-452AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PAH was raised in rabbit using the Recombinant Human Phenylalanine-4-hydroxylase protein (2-452AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human kidney tissue using PAH Antibody at dilution of 1:1002
| Cat.No | ADC-21736A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PAH |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phenylalanine-4-hydroxylase protein (2-452AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P00439 |
Uniprot Id
P00439
Target Species
Human
Target Name
PAH
Target Full Name
Phenylalanine-4-hydroxylase
Target Function
Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine.
Target Involvement
Phenylketonuria (PKU); Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA); Hyperphenylalaninemia (HPA)
Target Protein Families
Biopterin-dependent aromatic amino acid hydroxylase family
Target Research Area
Signal Transduction
Target Synonyms
PAH; PH; PH4H_HUMAN; Phe 4 monooxygenase; Phe-4-monooxygenase; Phenylalanine 4 hydroxylase; Phenylalanine hydroxylase; Phenylalanine-4-hydroxylase; PKU; PKU1
Target Background
This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
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