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Rabbit anti-Human PAOX Polyclonal Antibody

The antibody against PAOX was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PAOX. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-37249A

The antibody against PAOX was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PAOX. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-37249A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePaox
Target SynonymsPAOX antibody; PAO antibody; UNQ1923/PRO4398Peroxisomal N(1)-acetyl-spermine/spermidine oxidase antibody; EC 1.5.3.13 antibody; Polyamine oxidase antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human PAOX.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6QHF9
Background Information
  • Uniprot Id

    Q6QHF9

  • Target Species

    Human

  • Target Name

    PAOX

  • Target Full Name

    Peroxisomal N(1)-acetyl-spermine/spermidine oxidase

  • Target Function

    Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.

  • Target Subcellular Location

    Peroxisome. Cytoplasm.

  • Target Protein Families

    Flavin monoamine oxidase family

  • Target Tissue Specificity

    Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.

  • Target Synonyms

    PAOX; PAO; UNQ1923/PRO4398Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; EC 1.5.3.13; Polyamine oxidase

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