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The antibody against Papillary renal cell carcinoma was raised in Rabbit using a synthetic peptide of Human Papillary renal cell carcinoma as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against Papillary renal cell carcinoma was raised in Rabbit using a synthetic peptide of Human Papillary renal cell carcinoma as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08023A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Papillary renal cell carcinoma |
| Target Synonyms | TPRC; RCCP1; Papillary renal cell carcinoma | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide of Human Papillary renal cell carcinoma. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92733 |
Uniprot Id
Q92733
Target Species
Human
Target Name
PRCC
Target Full Name
Proline-rich protein PRCC
Target Function
May regulate cell cycle progression through interaction with MAD2L2.
Target Involvement
A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Ubiquitous in fetal and adult tissues.
Target Synonyms
Papillary renal cell carcinoma (Translocation associated); isoform CRA_b ; Papillary renal cell carcinoma translocation-associated gene protein; PRCC; PRCC_HUMAN; Proline rich protein PRCC; Proline-rich protein PRCC; RCCP1; TPRC
Target Background
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.
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