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The antibody against E2 was raised in rabbit using the Recombinant Human papillomavirus type 18 Regulatory protein E2 protein (1-365AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against E2 was raised in rabbit using the Recombinant Human papillomavirus type 18 Regulatory protein E2 protein (1-365AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-49741A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | E2 |
| Target Synonyms | E2 antibody; Regulatory protein E2 antibody | Form | Liquid |
| Species Reactivity | Human papillomavirus type 18 | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human papillomavirus type 18 Regulatory protein E2 protein (1-365AA) | Target Species | Human papillomavirus type 18 |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P06790 |
Uniprot Id
P06790
Target Species
Human papillomavirus type 18
Target Name
E2
Target Function
Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex.
Target Subcellular Location
Host nucleus.
Target Protein Families
Papillomaviridae E2 protein family
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