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The antibody against PARD6B was raised in rabbit using the Recombinant Human Partitioning defective 6 homolog beta protein (253-372AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against PARD6B was raised in rabbit using the Recombinant Human Partitioning defective 6 homolog beta protein (253-372AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human gastric cancer using PARD6B Antibody at dilution of 1:100
| Cat.No | ADC-16691A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PARD6B |
| Target Synonyms | PARD6B antibody; PAR6BPartitioning defective 6 homolog beta antibody; PAR-6 beta antibody; PAR-6B antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Partitioning defective 6 homolog beta protein (253-372AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BYG5 |
Uniprot Id
Q9BYG5
Target Species
Human
Target Name
PARD6B
Target Full Name
Partitioning defective 6 homolog beta
Target Function
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Target Subcellular Location
Cytoplasm. Cell membrane. Cell junction, tight junction.
Target Protein Families
PAR6 family
Target Tissue Specificity
Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Target Synonyms
PARD6B; PAR6BPartitioning defective 6 homolog beta; PAR-6 beta; PAR-6B
Target Background
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.
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