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The antibody against PENK was raised in rabbit using the Synthetic peptide from Human protein at AA range: 51-100 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against PENK was raised in rabbit using the Synthetic peptide from Human protein at AA range: 51-100 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of NT28 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:2002
Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:2003
| Cat.No | ADC-13071A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PENK |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 51-100 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01210 |
Uniprot Id
P01210
Target Species
Human
Target Name
PENK
Target Full Name
Proenkephalin-A
Target Function
Competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.; Competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.; Increases glutamate release in the striatum and decreases GABA concentration in the striatum.; Increases glutamate release in the striatum.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Secreted.
Target Protein Families
Opioid neuropeptide precursor family
Target Synonyms
Leu-enkephalin; Met-enkephalin; Met-enkephalin-Arg-Gly-Leu; Met-enkephalin-Arg-Phe; Methionine enkephalin; OGF; Opioid growth factor; PENK; PENK(114-133); PENK(143-183); PENK(237-258); PENK_HUMAN; PPA; Proenkephalin A; Proenkephalin; Proenkephalin-A; Synenkephalin
Target Background
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities.
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