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The antibody against PGA3 was raised in rabbit using the Recombinant Human Pepsin A-3 protein (16-388AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PGA3 was raised in rabbit using the Recombinant Human Pepsin A-3 protein (16-388AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-46271A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PGA3 |
| Target Synonyms | PGA3 antibody; Pepsin A-3 antibody; EC 3.4.23.1 antibody; Pepsinogen-3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Pepsin A-3 protein (16-388AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P0DJD8 |
Uniprot Id
P0DJD8
Target Species
Human
Target Name
PGA3
Target Full Name
Pepsin A-3
Target Function
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase A1 family
Target Synonyms
PGA3
Target Background
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
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