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The antibody against PHKG1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PHKG1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against PHKG1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PHKG1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of HepG2 cells using PHKG1 Polyclonal Antibody
Western Blot analysis of Jurkat K562 cells using PHKG1 Polyclonal Antibody2
| Cat.No | ADC-37861A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PHKG1 |
| Target Synonyms | gamma 1 (muscle) antibody; Phosphorylase kinase, gamma-1 antibody; Serine/threonine-protein kinase PHKG1 antibody; skeletal muscle/heart isoform antibody, muscle, skeletal muscle isoform antibody; phosphorylase kinase gamma antibody; phosphorylase kinase subunit gamma 1 antibody; Phosphorylase kinase subunit gamma-1 antibody; phosphorylase kinase | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human PHKG1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16816 |
Uniprot Id
Q16816
Target Species
Human
Target Name
PHKG1
Target Full Name
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
Target Function
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3.
Target Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Target Synonyms
PHK gamma M; PHK-gamma-M; Phkg; PHKG1; PHKG1_HUMAN; PHKIN01; Phosphorylase b kinase gamma catalytic chain; Phosphorylase b kinase gamma catalytic chain skeletal muscle/heart isoform; phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform ; phosphorylase kinase gamma ; phosphorylase kinase subunit gamma 1 ; Phosphorylase kinase subunit gamma-1; phosphorylase kinase, gamma 1 (muscle); Phosphorylase kinase, muscle, gamma-1; Serine/threonine-protein kinase PHKG1; skeletal muscle/heart isoform
Target Background
This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene.
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