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The antibody against PIK3R6 was raised in rabbit using the Recombinant Human Phosphoinositide 3-kinase regulatory subunit 6 protein (566-667AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PIK3R6 was raised in rabbit using the Recombinant Human Phosphoinositide 3-kinase regulatory subunit 6 protein (566-667AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-03287A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PIK3R6 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphoinositide 3-kinase regulatory subunit 6 protein (566-667AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5UE93 |
Uniprot Id
Q5UE93
Target Species
Human
Target Name
PIK3R6
Target Full Name
Phosphoinositide 3-kinase regulatory subunit 6
Target Function
Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS.
Target Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein.
Target Synonyms
C17orf38; Chromosome 17 open reading frame 38; HsT41028; p84 PI3K adapter protein; p84 PIKAP; p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein; p87 PI3K adapter protein; p87PIKAP; Phosphatidylinositol 3-kinase; regulatory subunit 6; Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; Phosphoinositide 3-kinase regulatory subunit 6; PI3Kgamma adapter protein of 87 kDa; PI3R6_HUMAN; PIK3R6
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