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The antibody against PKD1L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PKD1L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05349A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PKD1L2 |
| Target Synonyms | PC1L2; PKD1L2 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q7Z442 | Immunogen Sequence |
Uniprot Id
Q7Z442
Target Species
Human
Target Name
PKD1L2
Target Full Name
Polycystin-1-like protein 2
Target Function
May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Polycystin family
Target Tissue Specificity
Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.
Target Synonyms
PKD1L2; KIAA1879; PC1L2; Polycystic kidney disease protein 1-like 2; PC1-like 2 protein; Polycystin-1L2
Target Background
This gene encodes a member of the polycystin protein family. This protein may function as a G-protein-coupled component or regulator of cation channel pores. The long isoform of this protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene is a polymorphic pseudogene in humans.
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