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Rabbit anti-Human PLA2G4F Polyclonal Antibody

The antibody against PLA2G4F was raised in rabbit using the Recombinant Human Cytosolic phospholipase A2 zeta protein (74-299AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-01494A

The antibody against PLA2G4F was raised in rabbit using the Recombinant Human Cytosolic phospholipase A2 zeta protein (74-299AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-01494A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePLA2G4F
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Cytosolic phospholipase A2 zeta protein (74-299AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ68DD2
Background Information
  • Uniprot Id

    Q68DD2

  • Target Species

    Human

  • Target Name

    PLA2G4F

  • Target Full Name

    Cytosolic phospholipase A2 zeta

  • Target Function

    Has calcium-dependent phospholipase and lysophospholipase activities with a potential role in membrane lipid remodeling and biosynthesis of lipid mediators. Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis. In myocardial mitochondria, plays a major role in arachidonate release that is metabolically channeled to the formation of cardioprotective eicosanoids, epoxyeicosatrienoates (EETs).

  • Target Subcellular Location

    Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Mitochondrion.

  • Target Tissue Specificity

    Expressed in myocardium (at protein level).

  • Target Synonyms

    cPLA2-zeta; Cytosolic phospholipase A2 zeta; DKFZp666G192; DKFZp781B229; PA24F_HUMAN; Phospholipase A2 group IVF; Pla2g4f; PLA2G4FZ

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