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The antibody against PLEKHA8 was raised in rabbit using the Human PLEKHA8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PLEKHA8 was raised in rabbit using the Human PLEKHA8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-47604A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLEKHA8 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human PLEKHA8 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96JA3 |
Uniprot Id
Q96JA3
Target Species
Human
Target Name
PLEKHA8
Target Full Name
Pleckstrin homology domain-containing family A member 8
Target Function
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
Target Subcellular Location
Golgi apparatus, trans-Golgi network membrane. Membrane; Peripheral membrane protein.
Target Tissue Specificity
Expressed in kidney cell lines.
Target Synonyms
FAPP-2; FAPP2; hFAPP2; MGC3358; PH domain-containing family A member 8; Phosphatidylinositol-four-phosphate adapter protein 2; Phosphoinositide binding specificmember 8 ; Phosphoinositol 4 phosphate adaptor protein 2; Phosphoinositol 4-phosphate adapter protein 2; PKHA8_HUMAN; Pleckstrin homology domain containing A8; Pleckstrin homology domain containing family A (Phosphoinositide binding specific) member 8; Pleckstrin homology domain containing family A; Pleckstrin homology domain-containing family A member 8; Plekha8; PLEKHA8 protein ; Serologically defined breast cancer antigen NY-BR-86
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