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The antibody against PLEKHF1 was raised in rabbit using the Human PLEKHF1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against PLEKHF1 was raised in rabbit using the Human PLEKHF1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-47603A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLEKHF1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Human PLEKHF1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96S99 |
Uniprot Id
Q96S99
Target Species
Human
Target Name
PLEKHF1
Target Full Name
Pleckstrin homology domain-containing family F member 1
Target Function
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Target Subcellular Location
Nucleus. Cytoplasm, perinuclear region. Lysosome. Note=Translocates to lysosome during apoptosis.
Target Tissue Specificity
Highly expressed in heart and skeletal muscle. Weakly expressed in brain, thymus, spleen, kidney, liver, small intestine, placenta and lung.
Target Research Area
Others
Target Synonyms
PLEKHF1; APPD; LAPF; ZFYVE15; Pleckstrin homology domain-containing family F member 1; PH domain-containing family F member 1; Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains; Apoptosis-inducing protein; PH and FYVE domain-containing protein 1; Phafin-1; Zinc finger FYVE domain-containing protein 15
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