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The antibody against PLXDC1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TEM7. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against PLXDC1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TEM7. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-34429A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLXDC1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human TEM7. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IUK5 |
Uniprot Id
Q8IUK5
Target Species
Human
Target Name
PLXDC1
Target Full Name
Plexin domain-containing protein 1
Target Function
Plays a critical role in endothelial cell capillary morphogenesis.
Target Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; [Isoform 4]: Cytoplasm.
Target Protein Families
Plexin family
Target Tissue Specificity
Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased
Target Research Area
Cardiovascular
Target Synonyms
DKFZp686F0937 ; FLJ36270; FLJ45632; OTTHUMP00000164240; Plexin domain containing 1; Plexin domain containing protein 1 precursor; Plexin domain-containing protein 1; Plxdc1; PXDC1_HUMAN; TEM3; TEM7; Tumor endothelial marker 3; Tumor endothelial marker 7
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