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The antibody against PLXNB1 was raised in rabbit using the Recombinant Human Plexin-B1 protein (664-837AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PLXNB1 was raised in rabbit using the Recombinant Human Plexin-B1 protein (664-837AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-07299A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLXNB1 |
| Target Synonyms | PLXNB1 antibody; KIAA0407 antibody; PLXN5 antibody; SEP antibody; Plexin-B1 antibody; Semaphorin receptor SEP antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Plexin-B1 protein (664-837AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43157 |
Uniprot Id
O43157
Target Species
Human
Target Name
PLXNB1
Target Full Name
Plexin-B1
Target Function
Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Target Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.
Target Protein Families
Plexin family
Target Tissue Specificity
Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver.
Target Research Area
Neuroscience
Target Synonyms
PLXNB1; KIAA0407; PLXN5; SEP; Plexin-B1; Semaphorin receptor SEP
Target Background
Enables semaphorin receptor activity. Involved in several processes, including negative regulation of cell adhesion; regulation of cell shape; and semaphorin-plexin signaling pathway. Is integral component of plasma membrane. Part of semaphorin receptor complex.
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