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Rabbit anti-Human PNLIP Polyclonal Antibody

The antibody against PNLIP was raised in rabbit using the Fusion protein of Human PNLIP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-29539A

The antibody against PNLIP was raised in rabbit using the Fusion protein of Human PNLIP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-29539A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePNLIP
Target SynonymslipaseFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human PNLIPTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP16233
Background Information
  • Uniprot Id

    P16233

  • Target Species

    Human

  • Target Name

    PNLIP

  • Target Full Name

    Pancreatic triacylglycerol lipase

  • Target Function

    Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.

  • Target Involvement

    Pancreatic lipase deficiency (PNLIPD)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    AB hydrolase superfamily, Lipase family

  • Target Synonyms

    lipase, pancreatic; LIPP_HUMAN; Pancreatic lipase; Pancreatic triacylglycerol lipase; PL; PNLIP; PNLIPD; PTL; Triacylglycerol acylhydrolase

  • Target Background

    This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.

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